SIPA1 polyclonal antibody
产品名称： SIPA1 polyclonal antibody
英文名称： SIPA1 polyclonal antibody
产品编号： PAB6576
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of SIPA1.
- Immunogen:
- A synthetic peptide corresponding to human SIPA1.
- Sequence:
- C-ASKQLGSPTADLA
- Host:
- Goat
- Theoretical MW (kDa):
- 112
- Reactivity:
- Human
- Specificity:
- Both variants represent identical protein (NP_694985.28 and NP_006738.2).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Molecular cloning of a novel mitogen-inducible nuclear protein with a Ran GTPase-activating domain that affects cell cycle progression.
Hattori M, Tsukamoto N, Nur-e-Kamal MS, Rubinfeld B, Iwai K, Kubota H, Maruta H, Minato N.Mol Cell Biol. 1995 Jan;15(1):552-60.
- Entrez GeneID:
- 6494
- Protein Accession#:
- NP_694985.28;NP_006738.2
- Gene Name:
- SIPA1
- Gene Alias:
- MGC102688,MGC17037,SPA1
- Gene Description:
- signal-induced proliferation-associated 1
- Omim ID:
- 602180
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq
- Other Designations:
- GTPase-activating protein Spa-1,p130 SPA-1,signal-induced proliferation-associated gene 1,signal-induced proliferation-associated protein 1
- Gene Pathway