FITC标记的C型凝集素结构域家族4成员C抗体
产品名称： FITC标记的C型凝集素结构域家族4成员C抗体
英文名称： Anti-CLEC4C/FITC
产品编号： HZ-2568R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-CLEC4C/FITC Conjugated antibody
FITC标记的C型凝集素结构域家族4成员C抗体
| 英文名称 | Anti-CLEC4C/FITC |
| 中文名称 | FITC标记的C型凝集素结构域家族4成员C抗体 |
| 别 名 | CD303; CLC4C_HUMAN; BDCA-2; CLEC4C; BDCA2; BDCA-2; BDCA 2; Blood dendritic cell antigen 2; Blood dendritic cell antigen 2 protein; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 11; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 7; C-type lectin domain family 4 member C; C-type lectin domain family 4, member C, isoform 1; C-type lectin superfamily member 7; CD303; CD303 antigen; CLECSF11; CLECSF7; Dendritic cell lectin; dendritic cell lectin b; Dendritic lectin; DLEC; HECL; Lectin , C-type, superfamily member 11; MGC125789; MGC125791; MGC125792; MGC125793; PRO34150. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 细胞表面分子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 25kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CD303 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. Function: Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose. Subcellular Location: Membrane; Single-pass type II membrane protein (Probable). Tissue Specificity: Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha. Similarity: Contains 1 C-type lectin domain. Database links: UniProtKB/Swiss-Prot: Q8WTT0.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码C型凝集素/C型凝集素样结构域（CTL/CTLD）超家族成员。该家族成员具有共同的蛋白折叠，并具有不同的功能，如细胞粘附、细胞信号、糖蛋白周转、以及炎症和免疫应答中的作用。编码的2型跨膜蛋白可能在树突状细胞功能中发挥作用。已经鉴定了两个编码不同亚型的转录变体。[ RefSeq，JUL 2008 ]提供。