AXL (Human) Recombinant Protein
产品名称： AXL (Human) Recombinant Protein
英文名称： AXL (Human) Recombinant Protein
产品编号： P5687
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human AXL (NP_001690.2, 464 a.a. - 885 a.a.) partial recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells.
- Theoretical MW (kDa):
- 74
- Form:
- Liquid
- Preparation Method:
- Baculovirus expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 66 % by SDS-PAGE/CBB staining.
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
Substrate : CSKtide. ATP: 100 µM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 558
- Protein Accession#:
- NP_001690.2
- Gene Name:
- AXL
- Gene Alias:
- JTK11,UFO
- Gene Description:
- AXL receptor tyrosine kinase
- Omim ID:
- 109135
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- AXL transforming sequence/gene,oncogene AXL