IL10 monoclonal antibody, clone JES3-12G8
产品名称： IL10 monoclonal antibody, clone JES3-12G8
英文名称： IL10 monoclonal antibody, clone JES3-12G8
产品编号： MAB3286
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
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- 邮编 : 11493
- 所在区域 : 台湾
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- Specification
- Product Description:
- Rat monoclonal antibody raised against IL10.
- Immunogen:
- Human IL10.
- Host:
- Rat
- Reactivity:
- Human
- Specificity:
- human IL-10.
- Form:
- Liquid
- Isotype:
- IgG2a
- Storage Buffer:
- In 100 mM BBS, pH 8.2
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10.
Burdin N, Peronne C, Banchereau J, Rousset F.J Exp Med. 1993 Feb 1;177(2):295-304.
- 2.
- IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells.
Yssel H, De Waal Malefyt R, Roncarolo MG, Abrams JS, Lahesmaa R, Spits H, de Vries JE.J Immunol. 1992 Oct 1;149(7):2378-84.
- 3.
- Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.
Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE.Immunol Rev. 1992 Jun;127:5-24.
- Application Image
- Western Blot
- Entrez GeneID:
- 3586
- Gene Name:
- IL10
- Gene Alias:
- CSIF,IL-10,IL10A,MGC126450,MGC126451,TGIF
- Gene Description:
- interleukin 10
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq
- Other Designations:
- cytokine synthesis inhibitory factor
- Interactome
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Abscess
- Acidosis, Lactic
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Acute Lung Injury
- Adenocarcinoma
- Adenoma
- Adenomatous Polyps
- Adenovirus Infections, Human
- Aggressive Periodontitis
- AIDS-Related Opportunistic Infections
- Albuminuria
- Alcoholism
- alpha 1-Antitrypsin Deficiency
- Alpha-1-antitrypsin deficiency
- Alphavirus Infections
- Alveolar Bone Loss