MVK polyclonal antibody
产品名称： MVK polyclonal antibody
英文名称： MVK polyclonal antibody
产品编号： PAB4055
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MVK.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human MVK.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Molecular analysis of the MVK and TNFRSF1A genes in patients with a clinical presentation typical of the hyperimmunoglobulinemia D with periodic fever syndrome: a low-penetrance TNFRSF1A variant in a heterozygous MVK carrier possibly influences the phenotype of hyperimmunoglobulinemia D with periodic fever syndrome or vice versa.
Stojanov S, Lohse P, Lohse P, Hoffmann F, Renner ED, Zellerer S, Kery A, Shin YS, Haas D, Hoffmann GF, Belohradsky BH.Arthritis Rheum. 2004 Jun;50(6):1951-8.
- 2.
- Mevalonate kinase deficiency: Evidence for a phenotypic continuum.
Simon A, Kremer HP, Wevers RA, Scheffer H, De Jong JG, Van Der Meer JW, Drenth JP.Neurology. 2004 Mar 23;62(6):994-7.
- 3.
- Isolation and characterization of a novel trans-factor for luteinizing hormone receptor mRNA from ovary.
Nair AK, Menon KM.J Biol Chem. 2004 Apr 9;279(15):14937-44. Epub 2004 Jan 28.
- Entrez GeneID:
- 4598
- Protein Accession#:
- NP_000422
- Gene Name:
- MVK
- Gene Alias:
- FLJ96772,LRBP,MK,MVLK
- Gene Description:
- mevalonate kinase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- LH receptor mRNA-binding protein,mevalonic aciduria
- Related Disease
- Amyloidosis
- Autoimmune Diseases
- Behcet Syndrome
- Coronary Artery Disease
- Crohn's disease
- Diabetes Mellitus, Type 2
- Diarrhea
- Dyslipidemias
- Familial Mediterranean Fever
- Familial Mediterranean fever
- Genetic Predisposition to Disease
- Hyperlipidemias
- Hypertriglyceridemia
- Inflammation
- Irritable Bowel Syndrome
- Narcolepsy
- Pain
- Stomatitis, Aphthous
- Syndrome