FITC标记的核孔复合体蛋白88抗体
产品名称： FITC标记的核孔复合体蛋白88抗体
英文名称： Anti-NUP88/FITC
产品编号： HZ-10782R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NUP88/FITC Conjugated antibody
FITC标记的核孔复合体蛋白88抗体
| 英文名称 | Anti-NUP88/FITC |
| 中文名称 | FITC标记的核孔复合体蛋白88抗体 |
| 别 名 | karyoporin; Nuclear pore complex protein 88; Nuclear pore complex protein88; Nucleoporin 88; Nucleoporin 88 kDa; Nucleoporin 88kDa; Nucleoporin88; Nucleoporin88kDa; Nup 84; NUP 88; Nup84; Prei 2; Prei2; Preimplantation protein 2; Preimplantation protein2; NUP88_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 染色质和核信号 信号转导 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 85kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NUP88 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: NUP88 is a nucleoporin that is an essential component of the nuclear pore complex. It interacts with NUP214/CAN, and is phosphorylated following DNA damage, possibly via the ATM/ATR pathway. NUP88 is also a tumour marker as it is overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Function: Essential component of nuclear pore complex. Subunit: Interacts with NUP214/CAN. Subcellular Location: Nucleus, nuclear pore complex. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Database links: Entrez Gene: 4927 Human Entrez Gene: 19069 Mouse Entrez Gene: 113929 Rat Omim: 602552 Human SwissProt: Q99567 Human SwissProt: Q8CEC0 Mouse SwissProt: O08658 Rat Unigene: 584784 Human Unigene: 288962 Mouse Unigene: 11042 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
NUP88是核孔蛋白，是核孔复合体的重要组成部分。它与NUP214/CAN相互作用，并在DNA损伤后磷酸化，可能通过ATM/ATR途径。NUP88也是一种肿瘤标记物，因为它在大量的恶性肿瘤和癌前病变中过表达。