ERCC4 polyclonal antibody
产品名称： ERCC4 polyclonal antibody
英文名称： ERCC4 polyclonal antibody
产品编号： PAB17332
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ERCC4.
- Immunogen:
- A synthetic peptide corresponding to internal of human ERCC4.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Specificity:
- This antibody detects endogenous levels of total ERCC4 protein.
- Form:
- Liquid
- Storage Buffer:
- In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A summary of mutations in the UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy.
Cleaver JE, Thompson LH, Richardson AS, States JC.Hum Mutat. 1999;14(1):9-22.
- 2.
- ERCC4 (XPF) encodes a human nucleotide excision repair protein with eukaryotic recombination homologs.
Brookman KW, Lamerdin JE, Thelen MP, Hwang M, Reardon JT, Sancar A, Zhou ZQ, Walter CA, Parris CN, Thompson LH.Mol Cell Biol. 1996 Nov;16(11):6553-62.
- 3.
- Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease.
Sijbers AM, de Laat WL, Ariza RR, Biggerstaff M, Wei YF, Moggs JG, Carter KC, Shell BK, Evans E, de Jong MC, Rademakers S, de Rooij J, Jaspers NG, Hoeijmakers JH, Wood RD.Cell. 1996 Sep 6;86(5):811-22.
- Entrez GeneID:
- 2072
- Protein Accession#:
- Q92889
- Gene Name:
- ERCC4
- Gene Alias:
- RAD1,XPF
- Gene Description:
- excision repair cross-complementing rodent repair deficiency, complementation group 4
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6)
- Other Designations:
- excision-repair, complementing defective, in Chinese hamster,xeroderma pigmentosum, complementation group F
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenoma
- Alzheimer Disease
- Alzheimer disease
- Ataxia telangiectasia
- Bone Neoplasms
- Brain Neoplasms
- Breast cancer
- Breast Diseases
- Breast Neoplasms
- Carcinoma
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Cell Transformation, Neoplastic
- Chromosome Aberrations
- Cleft Lip
- Cleft Palate
- Colon cancer