HSPB8 monoclonal antibody (M05), clone 5G3
产品名称： HSPB8 monoclonal antibody (M05), clone 5G3
英文名称： HSPB8 monoclonal antibody (M05), clone 5G3
产品编号： H00026353-M05
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant HSPB8.
- Immunogen:
- HSPB8 (NP_055180, 97 a.a. ~ 196 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- KVCVNVHSFKPEELMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELPQDSQEVTCT
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG3 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of HSPB8 expression in transfected 293T cell line by HSPB8 monoclonal antibody (M05), clone 5G3.
Lane 1: HSPB8 transfected lysate(35.446 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Application Image
- Western Blot (Transfected lysate)
- enlarge
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 26353
- GeneBank Accession#:
- NM_014365
- Protein Accession#:
- NP_055180
- Gene Name:
- HSPB8
- Gene Alias:
- CMT2L,DHMN2,E2IG1,H11,HMN2,HMN2A,HSP22
- Gene Description:
- heat shock 22kDa protein 8
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq
- Other Designations:
- E2-induced gene 1,heat shock 27kDa protein 8,heat shock protein beta-8,protein kinase H11,small stress protein-like protein HSP22