FUT4 monoclonal antibody, clone MCS-1
产品名称: FUT4 monoclonal antibody, clone MCS-1
英文名称: FUT4 monoclonal antibody, clone MCS-1
产品编号: MAB4969
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against FUT4.
- Immunogen:
- X-hapten on lacto-N-fucose pentaosyl lll.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- The monoclonal antibody is directed against the CD15- antigen (the FAL structure) of human polymorphonuclear cells. The monoclonal antibody reacts with the promyelocytes, myelocytes and polymorphonuclear cells. After neuramidase treatment of cells the FAL structure is expressed on all cells of the monocytic and myelocytic lineage. This monoclonal antibody does not react with platelets and cells of the T and B lymphocyte lineage. The CD15 antigen is the X-hapten on lacto-N-fucose pentaosyl lll, which is expressed on circulating granulocytes or tissue granulocytes as well as neutrophils and eosinophils. The CD15 antibody recognizes the carbohydrate structure 3-fucosyl-N-acetyl-lactosamine. It specifically labels neutrophils, eosinophils and monoblastoid precursor cells of the myeloid lineage.
- Form:
- Liquid
- Isotype:
- IgG3
- Storage Buffer:
- In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Avoid prolonged exposure to light.
- Recommend Usage:
- Flow Cytometry (20 ul/106 cells)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Flow Cytometry
- This regent is effective for indirect immunofluorescence staining of normal peripheral blood from human for flow cytometric analysis using 0.5 ug/106 cells. Cell were analyzed on a FACSCalibur (Becton Dickinson, San Jose, CA) flow cytometer, using Cell Quest acquisition software and PAINT-A-GATE. PRO, analysis software.
- Entrez GeneID:
- 2526
- Gene Name:
- FUT4
- Gene Alias:
- CD15,ELFT,FCT3A,FUC-TIV,FUTIV
- Gene Description:
- fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
- Omim ID:
- 104230
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq
- Other Designations:
- ELAM ligand fucosyltransferase,fucosyltransferase 4,fucosyltransferase IV,galactoside 3-L-fucosyltransferase