TSHR Pre-design Chimera RNAi
产品名称： TSHR Pre-design Chimera RNAi
英文名称： TSHR Pre-design Chimera RNAi
产品编号： H00007253-R04
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Homo sapiens thyroid stimulating hormone receptor (TSHR), transcript variant 2, mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_001018036
- Target Region:
- Coding sequence
- Note:
- Position of the Chimera RNAi.
The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence. -
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 7253
- Gene Name:
- TSHR
- Gene Alias:
- CHNG1,LGR3,MGC75129,hTSHR-I
- Gene Description:
- thyroid stimulating hormone receptor
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- seven transmembrane helix receptor,thyroid stimulating hormone receptor, isoform 2,thyrotropin receptor,thyrotropin receptor-I, hTSHR-I
- Related Disease
- Abortion, Habitual
- Congenital Hypothyroidism
- Connective Tissue Diseases
- Fetal Diseases
- Genetic Predisposition to Disease
- Goiter, Nodular
- Graves Disease
- Graves Ophthalmopathy
- Hashimoto Disease
- Hypertension
- Hypothyroidism
- Infection
- Infertility, Female
- Inflammation
- Insulin Resistance
- Mitral Valve Prolapse
- Musculoskeletal Diseases
- Pancreatic cancer
- Pancreatic Neoplasms