MTRR (Human) Recombinant Protein (Q01)
产品名称： MTRR (Human) Recombinant Protein (Q01)
英文名称： MTRR (Human) Recombinant Protein (Q01)
产品编号： H00004552-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human MTRR partial ORF ( NP_002445, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MRRFLLLYATQQGQAKAIAEEMCEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKI
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 4552
- GeneBank Accession#:
- NM_002454
- Protein Accession#:
- NP_002445
- Gene Name:
- MTRR
- Gene Alias:
- MGC129643,MSR
- Gene Description:
- 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq
- Other Designations:
- [methionine synthase]-cobalamin methyltransferase (cob(II)alamin reducing),methionine synthase reductase
- Related Disease
- Abnormalities
- Abruptio Placentae
- Adenocarcinoma
- Adenoma
- Adrenoleukodystrophy
- Adrenoleukodystrophy
- Alcoholism
- Alzheimer disease
- Anemia, Iron-Deficiency
- Aortic Aneurysm, Abdominal
- Arthritis, Rheumatoid
- Atherosclerosis
- Atherosclerosis
- Autistic Disorder
- Avitaminosis
- Azoospermia
- Birth Weight
- Brain Ischemia
- Brain Neoplasms