FITC标记的DNAJC17蛋白抗体
产品名称： FITC标记的DNAJC17蛋白抗体
英文名称： Anti-DNAJC17/FITC
产品编号： HZ-14383R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DNAJC17/FITC Conjugated antibody
FITC标记的DNAJC17蛋白抗体
| 英文名称 | Anti-DNAJC17/FITC |
| 中文名称 | FITC标记的DNAJC17蛋白抗体 |
| 别 名 | DJC17_HUMAN; DnaJ (Hsp40) homolog subfamily C member 17; DnaJ homolog subfamily C member 17; DNAJC 17; DNAJC17; FLJ10634. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 转运蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DNAJC17 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The DnaJ family is one of the largest of all chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers, forming peptide binding domains responsible for chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DNAJC17 (DnaJ (Hsp40) homolog, subfamily C, member 17) is a 304 amino acid protein containing a J domain and a RRM (RNA recognition motif) domain. Similarity: Contains 1 J domain. Contains 1 RRM (RNA recognition motif) domain. Database links: Entrez Gene: 55192 Human Entrez Gene: 524795 Cow Entrez Gene: 478261 Dog Entrez Gene: 69408 Mouse Entrez Gene: 311329 Rat SwissProt: Q2KI83 Cow SwissProt: Q9NVM6 Human SwissProt: Q91WT4 Mouse Unigene: 511069 Human Unigene: 222241 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
DnaJ家族是所有伴侣分子家族中最大的家族之一，并具有不同的细胞定位和功能。J域的存在定义了作为DnaJ家族成员的蛋白质。DnaJ热休克诱导蛋白来源于大肠杆菌，受htpR调节蛋白的控制。DHNJ蛋白通过与HSP 70相互作用，在HSP 70伴侣机器中起关键作用，以刺激ATP水解。这些蛋白质含有由锌指组成的富含半胱氨酸的区域，形成负责伴侣功能的肽结合域。DnaJ蛋白是蛋白水解的重要介质，参与蛋白质降解、胞吐和胞内吞的调节。DNaJC17（DnaJ（HSP40）同源物，亚家族C，成员17）是含有J结构域和RRM（RN）的304氨基酸蛋白。