REL polyclonal antibody
产品名称： REL polyclonal antibody
英文名称： REL polyclonal antibody
产品编号： PAB14604
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of REL.
- Immunogen:
- A synthetic peptide corresponding to amino acids 10-28 of human REL.
- Sequence:
- IEIIEQPRQRGMRFRYKCE
- Host:
- Rabbit
- Reactivity:
- Chicken, Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:5000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Modulation of NF-kappaB activity by exchange of dimers.
Saccani S, Pantano S, Natoli G.Mol Cell. 2003 Jun;11(6):1563-74.
- 2.
- Regulation of c-Rel nuclear localization by binding of Ca2+/calmodulin.
Antonsson A, Hughes K, Edin S, Grundstrom T.Mol Cell Biol. 2003 Feb;23(4):1418-27.
- Application Image
- ELISA
- Entrez GeneID:
- 5966
- Protein Accession#:
- NP_002899
- Gene Name:
- REL
- Gene Alias:
- C-Rel
- Gene Description:
- v-rel reticuloendotheliosis viral oncogene homolog (avian)
- Omim ID:
- 164910
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM
- Other Designations:
- C-Rel proto-oncogene protein,oncogene REL, avian reticuloendotheliosis,v-rel avian reticuloendotheliosis viral oncogene homolog,v-rel reticuloendotheliosis viral oncogene homolog
- Related Disease
- Arthritis, Rheumatoid
- Cardiovascular Diseases
- Celiac Disease
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Edema
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hodgkin Disease
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Multiple Myeloma
- Occupational Diseases
- Psoriasis
- Waldenstrom Macroglobulinemia
- Werner syndrome