TIMP2 purified MaxPab mouse polyclonal antibody (B01P)
产品名称: TIMP2 purified MaxPab mouse polyclonal antibody (B01P)
英文名称: TIMP2 purified MaxPab mouse polyclonal antibody (B01P)
产品编号: H00007077-B01P
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human TIMP2 protein.
- Immunogen:
- TIMP2 (NP_003246.1, 1 a.a. ~ 220 a.a) full-length human protein.
- Sequence:
- MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of TIMP2 expression in transfected 293T cell line (H00007077-T01) by TIMP2 MaxPab polyclonal antibody.
Lane 1: TIMP2 transfected lysate(24.2 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Entrez GeneID:
- 7077
- GeneBank Accession#:
- NM_003255.4
- Protein Accession#:
- NP_003246.1
- Gene Name:
- TIMP2
- Gene Alias:
- CSC-21K
- Gene Description:
- TIMP metallopeptidase inhibitor 2
- Omim ID:
- 188825
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq
- Other Designations:
- tissue inhibitor of metalloproteinase 2,tissue inhibitor of metalloproteinases 2
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Aortic Aneurysm, Abdominal
- Arthritis, Rheumatoid
- Atherosclerosis
- Atrial Fibrillation
- Breast cancer
- Breast Neoplasms
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Carotid Artery Diseases
- Carotid Stenosis
- Cerebral Hemorrhage
- Chorioamnionitis
- Chronic Disease
- Cleft Lip
- Cleft Palate
- Colitis, Ulcerative
- Constriction, Pathologic